INT310172

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpine1) extracellular region (Serpine1)
Serpine1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 8 97.08 Very High Very High Very High
Melanoma 10 91.44 High High
Metastasis 24 90.72 High High
Cancer 110 85.76 High High
Osteolysis 2 79.36 Quite High
Anaplastic Astrocytoma 2 74.28 Quite High
Non-small-cell Lung Cancer 2 63.12 Quite High
Carcinoma 8 58.00 Quite High
Adenocarcinoma 4 56.00 Quite High
Myelodysplastic Syndromes 2 30.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect was due to blocked phosphorylation of SMADs leading to reduced transcription of PAI-1 and VEGF which are key mediators in cell invasion and neoangiogenesis [95].
Positive_regulation (leading) of Transcription (transcription) of PAI-1
1) Confidence 0.18 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2871186 Disease Relevance 0.99 Pain Relevance 0
This effect was due to blocked phosphorylation of SMADs leading to reduced transcription of PAI-1 and VEGF which are key mediators in cell invasion and neoangiogenesis [95].
Positive_regulation (mediators) of Transcription (transcription) of PAI-1
2) Confidence 0.13 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2871186 Disease Relevance 1.00 Pain Relevance 0

General Comments

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