INT310273

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Acaca) mitochondrion (Acaca) ligase activity (Acaca)
lipid metabolic process (Acaca) cytoplasm (Acaca)
Anatomy Link Frequency
muscle 1
Acaca (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 80.64 Quite High
fibrosis 2 50.84 Quite High
Inflammatory response 1 47.76 Quite Low
Chronic pancreatitis 1 32.16 Quite Low
tolerance 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Syndrome 35 87.04 High High
Lipodystrophy 1 86.08 High High
Insulin Resistance 20 82.72 Quite High
Coronary Artery Disease 1 81.52 Quite High
Obesity 11 75.28 Quite High
Hypertrophy 3 71.60 Quite High
Hyperplasia 2 70.96 Quite High
Hyperglycemia 3 65.52 Quite High
Impaired Glucose Tolerance 6 65.08 Quite High
Fibrosis 2 50.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low levels of adiponectin decrease fatty acid oxidation in the muscle, and this effect is mediated by the interaction with muscle and hepatic receptors through activation of AMP kinase, the cellular “fuel gauge”, which, in turn, inhibits acetyl CoA carboxylase and increases fatty acid beta-oxidation [30].
Negative_regulation (inhibits) of acetyl CoA carboxylase in muscle
1) Confidence 0.19 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872226 Disease Relevance 1.08 Pain Relevance 0.07

General Comments

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