INT310290

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.05
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Serpina10)
Anatomy Link Frequency
lung 3
Serpina10 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 4 94.60 High High
cytokine 52 92.32 High High
Inflammation 20 91.80 High High
Paracetamol 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 56 98.96 Very High Very High Very High
Hemorrhage 4 94.60 High High
Pressure And Volume Under Development 4 93.36 High High
INFLAMMATION 16 92.52 High High
Adult Respiratory Distress Syndrome 16 85.80 High High
Targeted Disruption 4 84.48 Quite High
Lung Injury 8 33.32 Quite Low
Body Weight 12 32.80 Quite Low
Injury 24 27.08 Quite Low
Stress 4 20.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of PZ pretreatment on iNOS gene expression in mouse lung after LPS
Positive_regulation (pretreatment) of PZ in lung
1) Confidence 0.02 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 0.25 Pain Relevance 0.08
Effect of PZ pretreatment on expression of HSP70 in mouse lung after LPS
Positive_regulation (pretreatment) of PZ in lung
2) Confidence 0.02 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 0.28 Pain Relevance 0.09
levels after LPS challenge, it is suggested that MT induction is not involved in the protective effect of PZ on LPS-induced endotoxin shock in our experimental model.
Positive_regulation (effect) of PZ associated with shock
3) Confidence 0.02 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 0.36 Pain Relevance 0.05
Therefore, we examined the effect of PZ pretreatment on the increase in MT-I and MT-II mRNA levels in the mouse lung after LPS administration.
Spec (examined) Positive_regulation (pretreatment) of PZ in lung
4) Confidence 0.02 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 0.16 Pain Relevance 0.03

General Comments

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