INT310311

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tlr4, Gpt) signal transduction (Tlr4) biosynthetic process (Gpt)
plasma membrane (Tlr4) intracellular (Tlr4)
Anatomy Link Frequency
plasma 1
Tlr4 (Mus musculus)
Gpt (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 90.48 High High
cytokine 13 55.36 Quite High
Inflammation 5 43.32 Quite Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 6 99.60 Very High Very High Very High
Adult Respiratory Distress Syndrome 4 95.08 Very High Very High Very High
Hepatotoxicity 1 89.60 High High
Multiple Organ Failure 3 89.56 High High
Endotoxemia 1 84.68 Quite High
Sepsis 1 83.92 Quite High
Death 3 83.52 Quite High
INFLAMMATION 4 43.32 Quite Low
Shock 14 13.76 Low Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPS increased plasma alanine aminotransferase (ALT) as an index of liver injury to just only 5-fold of normal level at 18 h after the injection (data not shown), although the ALT level was increased to several hundreds fold of normal level in the cases of lethal hepatic injuries such as acetaminophen-induced hepatotoxicity [28, 29].
LPS Positive_regulation (increased) of ALT in plasma associated with paracetamol, injury and hepatotoxicity
1) Confidence 0.05 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872229 Disease Relevance 1.15 Pain Relevance 0.12

General Comments

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