INT310369

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Trib3) nucleus (Trib3) enzyme binding (Trib3)
kinase activity (Trib3)
Trib3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
alcohol 10 71.28 Quite High
cytokine 1 70.92 Quite High
Inflammation 5 70.52 Quite High
fibrosis 2 68.52 Quite High
Neurotransmitter 1 28.40 Quite Low
Nucleus accumbens 6 14.76 Low Low
Chronic pancreatitis 10 5.00 Very Low Very Low Very Low
depression 9 5.00 Very Low Very Low Very Low
Cholecystokinin 5 5.00 Very Low Very Low Very Low
dopamine receptor 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 8 73.28 Quite High
INFLAMMATION 7 70.52 Quite High
Fibrosis 2 68.52 Quite High
Pancreatitis 47 52.28 Quite High
Pancreatic Cancer 17 51.44 Quite High
Alcoholic Pancreatitis 4 50.00 Quite Low
Pancreatic Ductal Carcinoma 1 48.64 Quite Low
Aggression 2 43.92 Quite Low
Injury 2 39.40 Quite Low
Shock 3 36.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/mL, ellagic acid inhibited PDGF-induced tyrosine phosphorylation of PDGF ß-receptor and the activation of the downstream signalling pathways (extracellular signal-regulated protein kinase and Akt).
Protein_catabolism (protein) of kinase
1) Confidence 0.01 Published 2010 Journal International Journal of Environmental Research and Public Health Section Body Doc Link PMC2872306 Disease Relevance 0.43 Pain Relevance 0.20
This is the first report stating that MIF-1 increases the phosphorylation of ERK, indicative of activation of a mitogen-activated protein kinase (MAPK) pathway.
Protein_catabolism (protein) of kinase
2) Confidence 0.01 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2915805 Disease Relevance 0 Pain Relevance 0

General Comments

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