INT310468

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Dlx2) nucleus (Dlx2) DNA binding (Dlx2)
Anatomy Link Frequency
ventral telencephalon 2
Dlx2 (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 40 98.52 Very High Very High Very High
cerebral cortex 28 25.72 Quite Low
imagery 10 5.00 Very Low Very Low Very Low
interneuron 8 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 18 99.32 Very High Very High Very High
Infection 37 43.36 Quite Low
Injury 11 5.00 Very Low Very Low Very Low
Stab Wounds 5 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Stuttering 2 5.00 Very Low Very Low Very Low
Vesicular Stomatitis 2 5.00 Very Low Very Low Very Low
Brain Injury 2 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As the homeobox transcription factor Dlx2 is one of the key factors involved in GABAergic neuron specification in the developing ventral telencephalon [13] and in adult neurogenesis [26], we examined whether forced expression of Dlx2 is also sufficient to induce a neuronal and possibly a GABAergic fate in cortical astroglia.
Spec (whether) Regulation (sufficient) of Gene_expression (expression) of Dlx2 in ventral telencephalon associated with gabaergic and neurodegenerative disease
1) Confidence 0.42 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2872647 Disease Relevance 0.10 Pain Relevance 0.18

General Comments

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