INT3107

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.54
First Reported 1978
Last Reported 2010
Negated 5
Speculated 0
Reported most in Abstract
Documents 11
Total Number 11
Disease Relevance 4.83
Pain Relevance 7.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Tst) RNA binding (Tst) plasma membrane (Tst)
Anatomy Link Frequency
plasma 1
tail 1
central nervous system 1
Tst (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 9 100.00 Very High Very High Very High
Morphine 40 99.84 Very High Very High Very High
withdrawal 26 99.84 Very High Very High Very High
agonist 9 99.82 Very High Very High Very High
Central nervous system 1 99.42 Very High Very High Very High
narcan 33 99.10 Very High Very High Very High
fluoxetine 2 99.04 Very High Very High Very High
Clonidine 6 98.98 Very High Very High Very High
Arthritis 1 98.96 Very High Very High Very High
antagonist 14 98.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Coronary Stenosis 1 99.80 Very High Very High Very High
Arthritis 1 98.96 Very High Very High Very High
Mycobacterial Infection 136 98.66 Very High Very High Very High
Disease 14 98.64 Very High Very High Very High
Rheumatoid Arthritis 4 98.32 Very High Very High Very High
Stress 4 97.80 Very High Very High Very High
Chronic Disease 2 96.64 Very High Very High Very High
Increased Venous Pressure Under Development 9 96.28 Very High Very High Very High
Myocardial Infarction 5 94.00 High High
Angina 4 91.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To evaluate the role of central nervous system (CNS) 5-HT(2A) receptors in TST regulation, DOI was administered in combination with a known peripheral 5-HT(2A/2C) receptor antagonist, xylamidine, in the MD model.
Regulation (regulation) of TST in central nervous system associated with antagonist and central nervous system
1) Confidence 0.54 Published 2004 Journal Brain Res. Section Abstract Doc Link 15527744 Disease Relevance 0.35 Pain Relevance 0.51
By contrast, multiple implants of E2 pellet (3 pellets over 3 weeks) did not affect the surge of TST.
Neg (not) Regulation (affect) of TST
2) Confidence 0.28 Published 1991 Journal Maturitas Section Abstract Doc Link 1907349 Disease Relevance 0.57 Pain Relevance 0.19
Although this mutation did not affect baseline extracellular serotonin levels or tail suspension test (TST) behavior, it enhanced fluoxetine effects on serotonin levels and immobility in the TST.
Neg (not) Regulation (affect) of TST in tail associated with serotonin and fluoxetine
3) Confidence 0.24 Published 2004 Journal Neuropsychopharmacology Section Abstract Doc Link 15138437 Disease Relevance 0.06 Pain Relevance 0.89
In contrast, an IV injection of 2.5 IU insulin (Na-porcine)/kg, which reduced plasma glucose for 2 h, caused a delayed TST response of 4.7 +/- 0.4 degrees C in control rats and exaggerated the TST response normally observed in morphine-dependent rats treated with naloxone.
Regulation (response) of TST in plasma associated with narcan and morphine
4) Confidence 0.24 Published 1990 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 2274603 Disease Relevance 0.26 Pain Relevance 1.08
Age affected TST only in patients without arthritis or life threatening disease.
Regulation (affected) of TST associated with disease and arthritis
5) Confidence 0.23 Published 1993 Journal J. Rheumatol. Section Abstract Doc Link 8441160 Disease Relevance 0.83 Pain Relevance 0.23
The majority of aged rats showed an exaggerated TST response to naloxone, while some aged rats failed to exhibit any TST response to withdrawal.
Regulation (response) of TST associated with narcan and withdrawal
6) Confidence 0.23 Published 1994 Journal Exp. Gerontol. Section Abstract Doc Link 8187842 Disease Relevance 0.47 Pain Relevance 1.02
Treatment with the alpha-adrenergic antagonist phentolamine (11.9 or 60 micrograms/rat, i.c.v.) failed to alter TST when administered alone, but the highest dose significantly reduced the TST response to naloxone in the morphine-dependent rat.
Neg (failed) Regulation (alter) of TST associated with antagonist, narcan and morphine
7) Confidence 0.23 Published 1987 Journal Brain Res. Section Abstract Doc Link 2825916 Disease Relevance 0 Pain Relevance 1.58
Intracerebroventricular (i.c.v.) injection of clonidine HCl, a partial alpha 2-adrenergic agonist did not alter TST in morphine-dependent animals.
Neg (not) Regulation (alter) of TST associated with agonist, intracerebroventricular, morphine and clonidine
8) Confidence 0.23 Published 1987 Journal Brain Res. Section Abstract Doc Link 2825916 Disease Relevance 0 Pain Relevance 1.30
Central administration of naloxone was without effect in controls but produced a 5-6 degree C rise of TST in the morphine-dependent rat while central administration of 10 microliters of the saline vehicle produced no changes in TST in either group.
Neg (no) Regulation (changes) of TST associated with narcan and morphine
9) Confidence 0.21 Published 1989 Journal Brain Res. Section Abstract Doc Link 2670064 Disease Relevance 0.20 Pain Relevance 0.68
When adjusting on age, sex and proximity to case, all factors independently associated with development of TB in contacts of TB cases [15], the hazard of developing TB was 1.5 greater when TST response was >10 mm and 2.6 greater when TST response was >15 mm.
Regulation (response) of TST associated with mycobacterial infection
10) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2865542 Disease Relevance 0.95 Pain Relevance 0
The sensitivities of MSPS and TST for coronary stenosis greater than or equal to 75% were 68% and 71%, respectively; their specificities were 97% and 79%, respectively (0.1 greater than p greater than 0.05).
Regulation (sensitivities) of TST associated with coronary stenosis
11) Confidence 0.04 Published 1978 Journal J. Nucl. Med. Section Abstract Doc Link 632901 Disease Relevance 1.13 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox