INT310703

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.68 Pain Relevance 0.21

structural constituent of ribosome (RPLP0) ribosome (RPLP0) intracellular (RPLP0) ribosome biogenesis (RPLP0) cytoplasm (RPLP0) cytosol (RPLP0)

Anatomy Link Frequency nervous system 2 RPLP0 (Homo sapiens)

Pain Link Frequency Relevance Heat diabetic neuropathy 2 77.72 Spinal cord 2 73.96 ischemia 1 73.24 Inflammation 4 67.92 Peripheral nervous system 5 67.20 carpal tunnel syndrome 38 50.00 gABA 4 35.92 antagonist 3 26.80 Sciatic nerve 1 10.04 Pain 10 5.00

Disease Link Frequency Relevance Heat Aging 2 99.14 Diabetes Mellitus 2 85.04 Diabetic Neuropathy 2 77.72 Disease 1 76.24 Cv Unclassified Under Development 1 73.24 Brain Injury 2 71.72 INFLAMMATION 5 67.92 Pressure And Volume Under Development 3 66.80 Apoptosis 1 65.76 Carpal Tunnel Syndrome 39 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Indeed aging nervous system, that is associated with a reduction in the synthesis of P0 and PMP22, appears to remain sensitive to some of progesterone's beneficial effects [34,35].

Negative_regulation (reduction) of Gene_expression (synthesis) of P0 in nervous system associated with aging

1) Confidence 0.04 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2873263 Disease Relevance 0.68 Pain Relevance 0.21

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