INT310891

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 28
Total Number 29
Disease Relevance 35.40
Pain Relevance 7.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
astrocytes 1
microglia 1
53T (Mus musculus)
53T - A53T (29)
Pain Link Frequency Relevance Heat
Glutamate 140 99.92 Very High Very High Very High
anesthesia 56 98.88 Very High Very High Very High
Spinal cord 476 97.88 Very High Very High Very High
Inflammation 112 96.80 Very High Very High Very High
cOX1 28 96.80 Very High Very High Very High
medulla 756 96.16 Very High Very High Very High
midbrain 368 96.08 Very High Very High Very High
cerebral cortex 224 94.08 High High
excitatory amino acid 56 92.56 High High
Inflammatory response 140 90.00 High High
Disease Link Frequency Relevance Heat
Targeted Disruption 3258 100.00 Very High Very High Very High
Disease 757 100.00 Very High Very High Very High
Stress 30 99.92 Very High Very High Very High
Paralysis 364 98.76 Very High Very High Very High
Movement Disorders 85 98.24 Very High Very High Very High
Death 28 97.64 Very High Very High Very High
Apoptosis 31 97.40 Very High Very High Very High
INFLAMMATION 252 96.80 Very High Very High Very High
Congenital Anomalies 112 96.56 Very High Very High Very High
Anaplastic Astrocytoma 28 96.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Astrocytic expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
1) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.07 Pain Relevance 0.26
To investigate whether over-expression of A53T ?
Spec (whether) Gene_expression (over) of A53T (A53T) associated with targeted disruption
2) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.81 Pain Relevance 0.18
Astrocytic expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
3) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.82 Pain Relevance 0.31
Moreover, at the cellular level, the expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
4) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.71 Pain Relevance 0.22
-syn on the neurological dysfunction, a cohort of A53T mice were administered with doxycycline (DOX), a tetracycline derivative, to block the expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption and anesthesia
5) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.64 Pain Relevance 0.10
To assess the impact of developmental expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
6) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.47 Pain Relevance 0.10
Astrocytic expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
7) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.58 Pain Relevance 0.29
Astrocytic expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
8) Confidence 0.50 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.78 Pain Relevance 0.37
Together, our findings demonstrate that astrocytic expression of PD-related A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption and disease
9) Confidence 0.43 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.57 Pain Relevance 0.38
Together these data indicate that astrocytic expression A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
10) Confidence 0.43 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.48 Pain Relevance 0.38
It is rather surprising to find that over-expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
11) Confidence 0.43 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.32 Pain Relevance 0.34
Astrocytic expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
12) Confidence 0.38 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.64 Pain Relevance 0.30
To investigate whether over-expression of A53T ?
Gene_expression (-) of A53T (A53T) associated with targeted disruption
13) Confidence 0.38 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.81 Pain Relevance 0.18
These data suggest that the paralysis developed by A53T mice is not dependent on the developmental expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption and paralysis
14) Confidence 0.38 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.71 Pain Relevance 0.29
To investigate whether over-expression of A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
15) Confidence 0.38 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.81 Pain Relevance 0.18
Alternatively, under the stress of excess A53T ?
Gene_expression (excess) of A53T (A53T) associated with targeted disruption and stress
16) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.81 Pain Relevance 0.46
-syn in astrocytes in determining the onset of behavioral and neuropathological phenotypes in A53T mice, we also examined the behavioral and neuropathological phenotypes of A53T-A8 mice (the low expression line).
Gene_expression (expression) of A53T-A8 (A53T) in astrocytes associated with targeted disruption
17) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.36 Pain Relevance 0.07
Taken to</span>gether, these results demonstrate that exogenous <span style="background-color:#B0E0E6">expression of human A53T ?
Gene_expression (expression) of A53T (A53T) associated with targeted disruption
18) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 0.86 Pain Relevance 0.38
We show here that the presence of excess A53T ?
Gene_expression (presence) of A53T (A53T) associated with targeted disruption
19) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.03 Pain Relevance 0.39
The A53T transgenic mice developed an early onset rapidly progressed movement disability
Gene_expression (transgenic mice) of A53T (A53T) associated with targeted disruption
20) Confidence 0.37 Published 2010 Journal Mol Brain Section Body Doc Link PMC2873589 Disease Relevance 1.80 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox