INT311041

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Acp5) lysosome (Acp5)
Anatomy Link Frequency
osteoclast 2
Acp5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 48.00 Quite Low
cytokine 2 43.20 Quite Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 4 92.60 High High
Osteoporosis 4 88.32 High High
Systemic Lupus Erythematosus 64 80.24 Quite High
Disease 10 68.40 Quite High
Bone Fracture 2 66.96 Quite High
Aplastic Anemia 2 64.80 Quite High
Graft Vs Host Disease 4 62.56 Quite High
Immune System Diseases 8 57.52 Quite High
Autoimmune Disease 8 50.48 Quite High
INFLAMMATION 6 48.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We compared SHED transplantation with BMMSC transplantation in inhibiting osteoclast activity in MRL/lpr mice and found that both SHED and BMMSC transplantation were able to reduce the number of tartrate-resistant acid phosphatase (TRAP)-positive osteoclasts in the distal femur epiphysis of MRL/lpr mice (Figure 6B), serum levels of runt-related NF-?
Negative_regulation (number) of TRAP in osteoclast
1) Confidence 0.09 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2873699 Disease Relevance 0.89 Pain Relevance 0
We compared SHED transplantation with BMMSC transplantation in inhibiting osteoclast activity in MRL/lpr mice and found that both SHED and BMMSC transplantation were able to reduce the number of tartrate-resistant acid phosphatase (TRAP)-positive osteoclasts in the distal femur epiphysis of MRL/lpr mice (Figure 6B), serum levels of runt-related NF-?
Negative_regulation (reduce) of TRAP in osteoclast
2) Confidence 0.09 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2873699 Disease Relevance 0.90 Pain Relevance 0

General Comments

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