INT31108

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Context Info
Confidence 0.55
First Reported 1987
Last Reported 1994
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrh, Gh1) extracellular region (Ghrh, Gh1) cytosol (Gh1)
signal transduction (Gh1) mitochondrion (Gh1) plasma membrane (Gh1)
Anatomy Link Frequency
plasma 1
pituitary 1
Ghrh (Rattus norvegicus)
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 13 99.50 Very High Very High Very High
Clonidine 4 98.20 Very High Very High Very High
anesthesia 1 88.68 High High
antagonist 1 85.32 High High
agonist 1 80.32 Quite High
Neuropeptide 1 28.72 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GHRH-ab significantly reduced plasma GH levels, and this effect was not altered by subsequent CLO administration.
GHRH-ab Negative_regulation (reduced) of GH in plasma associated with clonidine
1) Confidence 0.55 Published 1987 Journal Endocrinology Section Abstract Doc Link 2881775 Disease Relevance 0 Pain Relevance 0.76
These results suggest that neither pituitary GH depletion nor high somatostatin tone is involved in the GRF-induced GH inhibition.
GRF Negative_regulation (inhibition) of GH in pituitary associated with somatostatin
2) Confidence 0.44 Published 1994 Journal Life Sci. Section Abstract Doc Link 8277821 Disease Relevance 0 Pain Relevance 0.18

General Comments

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