INT311082

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (DST, MAPK8) nucleus (DST, MAPK8) nucleoplasm (MAPK8)
mitochondrion (MAPK8) nuclear envelope (DST) endoplasmic reticulum (DST)
DST (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 79.68 Quite High
GABA receptor 5 34.08 Quite Low
gABA 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
methadone 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 4 73.04 Quite High
Disease 35 50.00 Quite Low
Poisoning 1 48.48 Quite Low
Necrosis 8 5.00 Very Low Very Low Very Low
Breast Cancer 7 5.00 Very Low Very Low Very Low
Lung Cancer 6 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the human systems studied to date, BPA does not affect the proto-oncogene c-FOS (FOS) and the mitogen-activated protein kinase 8 (MAKP8) but seems to modify their expression in rodent species.
BPA Neg (not) Regulation (affect) of mitogen-activated protein kinase 8
1) Confidence 0.02 Published 2010 Journal PLoS Computational Biology Section Body Doc Link PMC2873901 Disease Relevance 0.07 Pain Relevance 0.04

General Comments

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