INT311135

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cxcr1) signal transducer activity (Cxcr1)
Anatomy Link Frequency
brain 2
Cxcr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 2 96.50 Very High Very High Very High
Neuronal excitability 1 89.68 High High
Inflammation 11 83.76 Quite High
chemokine 4 80.64 Quite High
Hippocampus 17 60.92 Quite High
cytokine 1 53.04 Quite High
Pyramidal cell 24 29.12 Quite Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Cannabinoid 4 5.00 Very Low Very Low Very Low
GABAergic 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 2 96.50 Very High Very High Very High
INFLAMMATION 12 83.76 Quite High
Status Epilepticus 57 75.76 Quite High
Injury 4 69.48 Quite High
Convulsion 18 65.44 Quite High
Apoptosis 8 40.44 Quite Low
Neurodegenerative Disease 1 33.32 Quite Low
Epilepsy 16 5.00 Very Low Very Low Very Low
Gliosis 4 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, a neutralizing anti-IL-8 antibody has significantly reduced ischemia-induced brain damage [66], further suggesting that inhibition of IL-8 binding to its receptor CXCR1 is another potential target for inhibiting the IL-8 effects [68], and the decreased CXCR1 expression may play a neuroprotective role.
Negative_regulation (decreased) of Gene_expression (expression) of CXCR1 in brain associated with ischemia
1) Confidence 0.48 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2873964 Disease Relevance 0.80 Pain Relevance 0.38

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox