INT311179

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.05
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CNR1, CNR2) signal transducer activity (CNR1, CNR2) aging (CNR1)
response to stress (CNR1)
Anatomy Link Frequency
leucocytes 4
CNR1 (Homo sapiens)
CNR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid 8 100.00 Very High Very High Very High
Endocannabinoid 100 84.48 Quite High
Migraine 2 5.00 Very Low Very Low Very Low
Cannabinoid receptor 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vomiting 158 99.20 Very High Very High Very High
Stress 76 89.76 High High
Obesity 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Headache 2 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cannabinoid-receptor 1 (CB1) but not cannabinoid-receptor 2 (CB2) mRNA expression in leucocytes 4 h after the experiment was significantly lower in volunteers with motion sickness than in participants without N&V.


CB1 Negative_regulation (lower) of Transcription (expression) of cannabinoid-receptor 2 in leucocytes associated with cannabinoid and vomiting
1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2873996 Disease Relevance 1.02 Pain Relevance 0.28
Cannabinoid-receptor 1 (CB1) but not cannabinoid-receptor 2 (CB2) mRNA expression in leucocytes 4 h after the experiment was significantly lower in volunteers with motion sickness than in participants without N&V.


CB1 Negative_regulation (lower) of Transcription ( mRNA expr) of CB2 in leucocytes associated with cannabinoid and vomiting
2) Confidence 0.41 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2873996 Disease Relevance 1.02 Pain Relevance 0.28

General Comments

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