INT311275

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Context Info
Confidence 0.34
First Reported 2010
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.33
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (Tnnt2) cytoplasm (Tnnt2)
Anatomy Link Frequency
Skeletal muscle 2
Tnnt2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 31 68.40 Quite High
anticonvulsant 1 30.48 Quite Low
Pain 1 28.88 Quite Low
antagonist 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
TRP channel 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 7 100.00 Very High Very High Very High
Chronic Renal Failure 26 98.64 Very High Very High Very High
Targeted Disruption 8 98.16 Very High Very High Very High
Myocardial Infarction 6 83.80 Quite High
Renal Disease 10 83.20 Quite High
Autosomal Dominant Polycystic Kidney 111 72.24 Quite High
Renal Insufficiency 2 62.16 Quite High
Muscle Disease 1 58.68 Quite High
Hypopituitarism 10 58.16 Quite High
Cardiovascular Disease 2 58.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of MBNL1 loss of function is reflected in Mbnl1 knockout mice that exhibit Skeletal muscle-specific chloride channel 1 (Clcn1), Cardiac troponin T (Tnnt2) and Skeletal troponin T (Tnnt3) splicing abnormalities characteristic of DM1 [16].
Regulation (abnormalities) of Gene_expression (splicing) of Tnnt2 in Skeletal muscle associated with targeted disruption and congenital anomalies
1) Confidence 0.34 Published 2010 Journal Current Chemical Genomics Section Body Doc Link PMC2874217 Disease Relevance 0.44 Pain Relevance 0
However, there are few studies describing the significance and the prognostic value of elevated serum cTnT levels in stable patients with moderate CKD [70].
Regulation (value) of Gene_expression (levels) of cTnT associated with chronic renal failure
2) Confidence 0.06 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3017903 Disease Relevance 0.89 Pain Relevance 0.10

General Comments

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