INT311276

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Mbnl1) RNA binding (Mbnl1) nucleus (Mbnl1)
cytoplasm (Mbnl1)
Anatomy Link Frequency
myoblast 2
Mbnl1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 4 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 5 96.72 Very High Very High Very High
Hypopituitarism 10 80.64 Quite High
Frailty 10 50.00 Quite Low
Cytomegalovirus Infection 1 48.32 Quite Low
Insulin Resistance 2 47.00 Quite Low
Arrhythmia Under Development 3 46.08 Quite Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Starvation 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore the immortalized DM1 myoblast cell line was found to retain the aberrant splicing and expression loss of MBNL1/CUGBP1 target genes, and the myogenic differentiation defect associated with the disease.
Negative_regulation (loss) of Gene_expression (expression) of MBNL1 in myoblast associated with disease
1) Confidence 0.37 Published 2010 Journal Current Chemical Genomics Section Body Doc Link PMC2874217 Disease Relevance 0.32 Pain Relevance 0

General Comments

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