INT311291

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (MBNL1) RNA binding (MBNL1) nucleus (MBNL1)
cytoplasm (MBNL1)
MBNL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 4 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
anticonvulsant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myotonic Dystrophy 2 93.04 High High
Hyperinsulinism 1 88.60 High High
Arrhythmia Under Development 3 87.92 High High
Cataract 2 87.12 High High
Hypopituitarism 10 86.68 High High
Frailty 10 86.28 High High
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Starvation 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The DMPK transcripts containing expanded CUG repeats accumulate in nuclear foci and ultimately cause mis-splicing of secondary genes through the dysregulation of RNA-binding proteins including Muscleblind 1 (MBNL1) and CUG binding protein 1 (CUGBP1).
Regulation (dysregulation) of Muscleblind 1
1) Confidence 0.02 Published 2010 Journal Current Chemical Genomics Section Abstract Doc Link PMC2874217 Disease Relevance 0.69 Pain Relevance 0

General Comments

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