INT311322

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Context Info
Confidence 0.55
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Celf1) mRNA processing (Celf1) RNA binding (Celf1)
nucleus (Celf1) cytoplasm (Celf1)
Celf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 32 89.00 High High
Targeted Disruption 38 84.48 Quite High
Congenital Anomalies 22 55.88 Quite High
Myotonic Dystrophy 44 50.00 Quite Low
Disease 26 50.00 Quite Low
Myotonia 28 5.00 Very Low Very Low Very Low
Cataract 14 5.00 Very Low Very Low Very Low
Frailty 14 5.00 Very Low Very Low Very Low
Aging 10 5.00 Very Low Very Low Very Low
Muscular Atrophy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since CUGBP1 mRNA levels are not increased in DM1 cells, it was suggested that CUG repeats may increase CUGBP1 stability.
Transcription (levels) of CUGBP1
1) Confidence 0.55 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.08 Pain Relevance 0
In patients with DM1, CUGBP1 protein is increased without significant changes of CUGBP1 transcripts levels [39].
Transcription (transcripts) of CUGBP1
2) Confidence 0.43 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.29 Pain Relevance 0

General Comments

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