INT311334

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Dmpk) mitochondrion (Dmpk) endoplasmic reticulum (Dmpk)
plasma membrane (Dmpk) nucleus (Dmpk) kinase activity (Dmpk)
Dmpk (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 13 95.08 Very High Very High Very High
Myotonia 14 72.88 Quite High
Arrhythmias 2 Under Development 2 71.44 Quite High
Targeted Disruption 19 69.96 Quite High
Frailty 7 69.60 Quite High
Cataract 7 67.36 Quite High
Myotonic Dystrophy 22 50.00 Quite Low
Toxicity 16 48.92 Quite Low
Congenital Anomalies 11 5.00 Very Low Very Low Very Low
Aging 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several recent reports suggest that the nuclear aggregates of the mutant DMPK mRNA are not sufficient to cause DM1 phenotype.
Positive_regulation (cause) of Localization (aggregates) of mutant DMPK mRNA
1) Confidence 0.38 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.76 Pain Relevance 0

General Comments

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