INT311389

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.59
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Celf1) mRNA processing (Celf1) RNA binding (Celf1)
nucleus (Celf1) translation (Eif2s2) cytoplasm (Celf1)
Anatomy Link Frequency
myoblasts 2
muscle 2
Celf1 (Mus musculus)
Eif2s2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 38 75.92 Quite High
Myotonic Dystrophy 44 69.60 Quite High
Congenital Anomalies 22 66.20 Quite High
Disease 26 50.00 Quite Low
Stress 2 49.60 Quite Low
Toxicity 32 5.00 Very Low Very Low Very Low
Myotonia 28 5.00 Very Low Very Low Very Low
Cataract 14 5.00 Very Low Very Low Very Low
Frailty 14 5.00 Very Low Very Low Very Low
Aging 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that the interaction of CUGBP1 with eIF2 is increased during normal muscle differentiation [78].
Positive_regulation (increased) of CUGBP1 Binding (interaction) of eIF2 in muscle
1) Confidence 0.17 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.20 Pain Relevance 0
Ectopic expression of cyclin D3 promoted the formation of the CUGBP1-eIF2 complex in DM1 myotubes and improved fusion of DM1 myoblasts [78].
Positive_regulation (promoted) of CUGBP1 Binding (complex) of eIF2 in myoblasts
2) Confidence 0.10 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.39 Pain Relevance 0

General Comments

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