INT311390

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Mbnl1, Celf1) RNA binding (Mbnl1, Celf1) nucleus (Mbnl1, Celf1)
cytoplasm (Mbnl1, Celf1) mRNA binding (Celf1)
Mbnl1 (Mus musculus)
Celf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 19 90.56 High High
Frailty 7 86.00 High High
Arrhythmias 2 Under Development 2 80.44 Quite High
Myotonia 14 79.32 Quite High
Disease 13 58.04 Quite High
Myotonic Dystrophy 22 50.00 Quite Low
Cataract 7 30.32 Quite Low
Toxicity 16 11.88 Low Low
Congenital Anomalies 11 5.00 Very Low Very Low Very Low
Aging 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on these results, it is reasonable to suggest that DM1 phenotype could be caused equally well by the reduction of MBNL1 and by the increase of CUGBP1.
MBNL1 Positive_regulation (increase) of CUGBP1
1) Confidence 0.26 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.48 Pain Relevance 0

General Comments

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