INT311399

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Uts2r) mRNA binding (Celf1) mRNA processing (Celf1)
RNA binding (Celf1) plasma membrane (Uts2r) nucleus (Celf1)
Anatomy Link Frequency
poly 1
Celf1 (Mus musculus)
Uts2r (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 97.56 Very High Very High Very High
Inflammation 1 66.96 Quite High
Central nervous system 2 5.00 Very Low Very Low Very Low
spastic colon 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 98.36 Very High Very High Very High
Cancer 1 98.00 Very High Very High Very High
INFLAMMATION 1 66.96 Quite High
Myotonic Dystrophy 22 50.00 Quite Low
Disease 13 50.00 Quite Low
Frailty 7 47.28 Quite Low
Insulin Resistance 3 45.76 Quite Low
Toxicity 16 8.96 Low Low
Targeted Disruption 19 5.00 Very Low Very Low Very Low
Myotonia 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that CUGBP1 binds to the 3’ UTR of TNF mRNA and destabilizes it through the direct interaction with poly A ribonuclease (PARN) removing the poly(A) tail [80].
CUGBP1 Binding (binds) of UTR in poly
1) Confidence 0.08 Published 2010 Journal Current Genomics Section Body Doc Link PMC2874224 Disease Relevance 0.26 Pain Relevance 0.12

General Comments

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