INT311432

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TAOK1) plasma membrane (TSHR) kinase activity (TAOK1)
cytoplasm (TAOK1) cell-cell signaling (TSHR) signal transducer activity (TSHR)
TSHR (Homo sapiens)
TAOK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 74.00 Quite High
Pain 1 12.60 Low Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 11 87.48 High High
Graves' Ophthalmopathy 31 87.12 High High
Thyroid Disease 22 86.40 High High
Hypothyroidism 1 85.08 High High
Obesity 1 80.24 Quite High
INFLAMMATION 9 74.00 Quite High
Muscle Disease 12 70.32 Quite High
Thyroiditis 33 70.00 Quite High
Ocular & Orbital Inflammation 3 63.16 Quite High
Hyperthyroidism 4 61.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the evidence provides strong overall support for a role of the TSH-r in the pathogenesis of TAO, whether TSH-r antibodies are really linked to ophthalmopathy in all cases of TAO remains unclear.
TSH-r Binding (linked) of TAO
1) Confidence 0.12 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 1.05 Pain Relevance 0.07

General Comments

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