INT311441

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.00
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (COL13A1) plasma membrane (COL13A1)
Anatomy Link Frequency
fibroblast 1
connective tissue 1
COL13A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 26 87.04 High High
Pain 2 13.12 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 44 89.16 High High
Disease 22 87.80 High High
Graves' Ophthalmopathy 62 87.44 High High
INFLAMMATION 18 87.04 High High
Myasthenia Gravis 2 70.56 Quite High
Thyroid Disease 44 56.84 Quite High
Muscle Disease 24 52.56 Quite High
Thyroiditis 66 38.84 Quite Low
Hyperthyroidism 8 34.96 Quite Low
Pressure And Volume Under Development 4 33.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The main antibodies proposed are those targeting i) the flavoprotein (Fp) subunit of mitochondrial succinate dehydrogenase; ii) G2s, shown to be a fragment of the FOX-P1 transcription factor; iii) the calcium binding protein calsequestrin; and iv) collagen XIII, a connective tissue antigen expressed in the orbital fibroblast cell membranes.
collagen XIII Binding (binding) of in fibroblast
1) Confidence 0.11 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 0.45 Pain Relevance 0
At that time we were also interested in the connective tissue antigen collagen XIII because serum antibodies against collagen XIII were shown to be good markers of ophthalmopathy in patients with active ophthalmopathy.33
collagen XIII Binding (interested) of in connective tissue
2) Confidence 0.10 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 0.55 Pain Relevance 0.04

General Comments

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