INT311453

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.44
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CASQ1) Golgi apparatus (CASQ1) endoplasmic reticulum (CASQ1)
cytoplasm (CASQ1)
Anatomy Link Frequency
fibroblast 1
CASQ1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 41.44 Quite Low
Pain 1 11.28 Low Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 22 89.16 High High
Thyroid Disease 22 56.84 Quite High
Graves' Ophthalmopathy 31 56.16 Quite High
Muscle Disease 12 50.72 Quite High
INFLAMMATION 9 41.44 Quite Low
Thyroiditis 33 38.84 Quite Low
Pressure And Volume Under Development 2 31.84 Quite Low
Exophthalmos 2 26.24 Quite Low
Hyperthyroidism 4 19.64 Low Low
Disease 11 17.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The main antibodies proposed are those targeting i) the flavoprotein (Fp) subunit of mitochondrial succinate dehydrogenase; ii) G2s, shown to be a fragment of the FOX-P1 transcription factor; iii) the calcium binding protein calsequestrin; and iv) collagen XIII, a connective tissue antigen expressed in the orbital fibroblast cell membranes.
calsequestrin Binding (binding) of in fibroblast
1) Confidence 0.31 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 0.44 Pain Relevance 0

General Comments

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