INT311455

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.00
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (COL13A1) plasma membrane (COL13A1)
Anatomy Link Frequency
connective tissue 2
LPS 2
COL13A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 26 84.16 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 44 95.04 Very High Very High Very High
Thyroid Disease 44 87.72 High High
Disease 22 84.92 Quite High
Thyroiditis 66 84.84 Quite High
Graves' Ophthalmopathy 62 84.56 Quite High
INFLAMMATION 18 84.16 Quite High
Eyelid Disease 2 79.04 Quite High
Hyperthyroidism 8 73.12 Quite High
Myasthenia Gravis 2 67.68 Quite High
Injury 2 64.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Type XIII collagen, expressed in fibroblast cell membranes, is also widely expressed in the adult and developing human eye.36 Although yet to be proven by histological analysis, our findings suggest that chronic UER and lag may reflect autoimmunity against calsequestrin and collagen XIII in the LPS muscle.


Negative_regulation (developing) of Gene_expression (expressed) of Type XIII collagen in LPS associated with autoimmune disease
1) Confidence 0.13 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 1.30 Pain Relevance 0
At that time we were also interested in the connective tissue antigen collagen XIII because serum antibodies against collagen XIII were shown to be good markers of ophthalmopathy in patients with active ophthalmopathy.33
Negative_regulation (markers) of Gene_expression (antibodies) of collagen XIII in connective tissue
2) Confidence 0.13 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2874268 Disease Relevance 0.69 Pain Relevance 0.04

General Comments

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