INT311519

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2d) plasma membrane (Grin2d)
Anatomy Link Frequency
cerebral cortex 2
Grin2d (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 12 98.44 Very High Very High Very High
Hippocampus 69 96.60 Very High Very High Very High
nMDA receptor 129 96.24 Very High Very High Very High
Glutamate 24 77.84 Quite High
long-term potentiation 26 5.00 Very Low Very Low Very Low
antagonist 20 5.00 Very Low Very Low Very Low
agonist 13 5.00 Very Low Very Low Very Low
depression 9 5.00 Very Low Very Low Very Low
Glutamate receptor 7 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 114 86.68 High High
Sprains And Strains 7 82.76 Quite High
Urological Neuroanatomy 14 49.84 Quite Low
Cognitive Disorder 25 5.00 Very Low Very Low Very Low
Depression 9 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In aged C57BL/6 mice, the mRNA expression of the GluN2B subunit declines significantly with age throughout the cerebral cortex and in some subregions of the hippocampus (Magnusson, 2000, 2001; Ontl et al., 2004; Magnusson et al., 2006).
Negative_regulation (declines) of Transcription (expression) of GluN2B in cerebral cortex associated with hippocampus and cerebral cortex
1) Confidence 0.02 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874396 Disease Relevance 0.45 Pain Relevance 0.40

General Comments

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