INT311531

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) mitochondrion (IMMT)
plasma membrane (ROS1) biological_process (IMMT)
Anatomy Link Frequency
neurons 2
IMMT (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 12 94.28 High High
Dopamine 5 86.48 High High
Hippocampus 8 68.72 Quite High
Inflammatory response 6 57.92 Quite High
Central nervous system 11 39.68 Quite Low
Neurotransmitter 3 32.56 Quite Low
cytokine 2 7.28 Low Low
Glutamate 17 5.00 Very Low Very Low Very Low
Substantia nigra 12 5.00 Very Low Very Low Very Low
long-term potentiation 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 143 100.00 Very High Very High Very High
Injury 3 94.88 High High
Cv Unclassified Under Development 11 94.28 High High
Brain Injury 1 90.16 High High
Disease 34 86.72 High High
Apoptosis 6 78.16 Quite High
Death 13 62.80 Quite High
Pressure And Volume Under Development 1 61.76 Quite High
INFLAMMATION 10 57.92 Quite High
Parkinson's Disease 10 50.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This mitochondrial inner membrane protein can protect neurons from OS by reducing ROS production through the uncoupling of oxidative phosphorylation and ATP synthesis (Horvath et al., 2003).
mitochondrial inner membrane protein Negative_regulation (reducing) of Gene_expression (production) of ROS in neurons associated with stress
1) Confidence 0.11 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874397 Disease Relevance 1.09 Pain Relevance 0.24

General Comments

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