INT311532

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) plasma membrane (ROS1)
transmembrane transport (RYR3)
ROS1 (Homo sapiens)
RYR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 11 96.52 Very High Very High Very High
Substantia nigra 12 40.16 Quite Low
Ventral tegmentum 9 34.92 Quite Low
midbrain 2 27.36 Quite Low
Glutamate 17 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
Central nervous system 11 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 143 65.60 Quite High
Apoptosis 6 56.40 Quite High
Death 13 11.72 Low Low
Disease 34 5.00 Very Low Very Low Very Low
Aging 16 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low
Parkinson's Disease 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The modulation of RyR3 activity by ROS leads to the activation of downstream factors, including ERK and CREB.
ROS Regulation (modulation) of RyR3
1) Confidence 0.43 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874397 Disease Relevance 0.18 Pain Relevance 0.25

General Comments

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