INT311533

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) plasma membrane (ROS1)
transmembrane transport (RYR3)
ROS1 (Homo sapiens)
RYR3 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 11 100.00 Very High Very High Very High
Ventral tegmentum 9 39.32 Quite Low
Substantia nigra 12 33.04 Quite Low
midbrain 2 31.76 Quite Low
Glutamate 17 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
Central nervous system 11 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 143 65.72 Quite High
Apoptosis 6 49.28 Quite Low
Death 13 16.12 Low Low
Disease 34 5.00 Very Low Very Low Very Low
Aging 16 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low
Parkinson's Disease 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ROS-induced form of LTP requires the activation of RyR3, a subtype of the RyRs (Huddleston et al., 2008).
ROS Positive_regulation (requires) of Positive_regulation (activation) of RyR3 associated with long-term potentiation
1) Confidence 0.28 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874397 Disease Relevance 0.18 Pain Relevance 0.26

General Comments

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