INT311534

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CISH, NFE2L2) intracellular (CISH) DNA binding (NFE2L2)
cytoplasm (NFE2L2) nucleus (NFE2L2) plasma membrane (NFE2L2)
CISH (Homo sapiens)
NFE2L2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Ventral tegmentum 9 26.00 Quite Low
midbrain 2 23.76 Low Low
Glutamate 17 5.00 Very Low Very Low Very Low
Substantia nigra 12 5.00 Very Low Very Low Very Low
ischemia 12 5.00 Very Low Very Low Very Low
long-term potentiation 11 5.00 Very Low Very Low Very Low
Central nervous system 11 5.00 Very Low Very Low Very Low
Hippocampus 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Dopamine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 143 92.56 High High
Death 13 54.80 Quite High
Disease 34 5.00 Very Low Very Low Very Low
Aging 16 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 11 5.00 Very Low Very Low Very Low
Parkinson's Disease 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nrf2 activates the transcription of a multitude of downstream anti-oxidant genes via binding to the cis-acting anti-oxidant response element (ARE) of these genes (Nguyen et al., 2004).
cis-acting Binding (binding) of Nrf2
1) Confidence 0.02 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874397 Disease Relevance 0.64 Pain Relevance 0

General Comments

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