INT311612

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Drd2) plasma membrane (Drd2) signal transducer activity (Drd2)
Drd2 (Rattus norvegicus)
Sert1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 6 100.00 Very High Very High Very High
cocaine 39 99.58 Very High Very High Very High
Eae 18 87.92 High High
Cannabinoid receptor 3 85.52 High High
Migraine 1 78.76 Quite High
headache 1 78.24 Quite High
agonist 1 76.52 Quite High
Serotonin 11 50.00 Quite Low
Somatosensory cortex 1 15.60 Low Low
Pyramidal cell 1 11.44 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 23 93.48 High High
Increased Venous Pressure Under Development 2 82.36 Quite High
Headache 2 78.76 Quite High
Apoptosis 3 65.44 Quite High
Adhesions 2 54.40 Quite High
Targeted Disruption 6 50.00 Quite Low
Obesity 30 27.48 Quite Low
Sprains And Strains 13 5.00 Very Low Very Low Very Low
Hypertension 7 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The dopamine D2 receptor mediates both the rewarding and anxiogenic effects of cocaine [31], and there are interactions between the dopamine D2 receptor and SERT in mediating cocaine reward [32], both of which may modify SERT-/- rat behavioral responses to cocaine.
dopamine D2 receptor Binding (interactions) of SERT associated with dopamine and cocaine
1) Confidence 0.12 Published 2010 Journal BMC Genet Section Body Doc Link PMC2874760 Disease Relevance 0.65 Pain Relevance 0.86

General Comments

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