INT311636

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc12a3) transport (Slc12a3) plasma membrane (Slc12a3)
transmembrane transport (Slc12a3)
Anatomy Link Frequency
embryos 2
second branchial arch 2
Slc12a3 (Mus musculus)
Pain Link Frequency Relevance Heat
vagus nerve 2 35.20 Quite Low
midbrain 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 38 100.00 Very High Very High Very High
Congenital Anomalies 14 93.84 High High
Syndrome 2 82.92 Quite High
Craniosynostosis 2 82.52 Quite High
Cleft Palate 16 76.72 Quite High
"congenital, Hereditary, And Neonatal Diseases And Abnormalities" 2 21.12 Low Low
Targeted Disruption 54 18.28 Low Low
Persistent Truncus Arteriosus 8 5.00 Very Low Very Low Very Low
Ventricular Heart Septal Defects 8 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While it is likely that increased proliferation and decreased apoptosis in NCC of Spry1;Wnt1-Cre embryos contributes to the phenotype, it is also possible that similar to the Pdgfr?
Positive_regulation (increased) of Gene_expression (embryos) of NCC in embryos associated with apoptosis
1) Confidence 0.23 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.37 Pain Relevance 0
A hypomorphic allele of Fgfr1 has been used to demonstrate that FGFR1 is required for NCC migration into the second branchial arch [8].
Positive_regulation (required) of Gene_expression (migration) of NCC in second branchial arch
2) Confidence 0.23 Published 2010 Journal BMC Dev Biol Section Body Doc Link PMC2874773 Disease Relevance 0.26 Pain Relevance 0

General Comments

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