INT311708

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Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Col17a1) cellular_component (Col17a1) biological_process (Col17a1)
Anatomy Link Frequency
mast cell 2
Col17a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 2 92.48 High High
metalloproteinase 1 78.72 Quite High
ischemia 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 57 93.84 High High
Pressure And Volume Under Development 2 93.00 High High
Cv General 3 Under Development 1 92.48 High High
Hemorrhage 1 81.08 Quite High
Middle Cerebral Artery Infarction 31 44.72 Quite Low
Injury 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our study, we identified a number of genes differentially regulated by tPA that affect mast cells, including those involved in mast cell activation (FCGR2B) and mast cell degranulation (COL17A, PIK3CD, ORAI1).
Positive_regulation (activation) of Protein_catabolism (degranulation) of COL17A in mast cell
1) Confidence 0.30 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2875237 Disease Relevance 0.69 Pain Relevance 0.13

General Comments

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