INT311727

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.71
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Plat, Col17a1) peptidase activity (Plat) extracellular space (Plat)
extracellular region (Plat) cellular_component (Col17a1) biological_process (Col17a1)
Anatomy Link Frequency
mast cell 2
Plat (Rattus norvegicus)
Col17a1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 2 95.64 Very High Very High Very High
metalloproteinase 1 78.72 Quite High
ischemia 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 2 96.16 Very High Very High Very High
Cv General 3 Under Development 1 95.64 Very High Very High Very High
Stroke 57 93.84 High High
Hemorrhage 1 84.24 Quite High
Middle Cerebral Artery Infarction 31 44.72 Quite Low
Injury 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Cv General 4 Under Development 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our study, we identified a number of genes differentially regulated by tPA that affect mast cells, including those involved in mast cell activation (FCGR2B) and mast cell degranulation (COL17A, PIK3CD, ORAI1).
tPA Regulation (regulated) of in mast cells Protein_catabolism (degranulation) of COL17A in mast cell
1) Confidence 0.31 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2875237 Disease Relevance 0.71 Pain Relevance 0.13

General Comments

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