INT311750

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCB1) ATPase activity (ABCB1) plasma membrane (ABCB1)
transmembrane transport (ABCB1)
ABCB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 1 55.12 Quite High
IPN 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 4 69.00 Quite High
Lung Cancer 1 41.60 Quite Low
Malignant Neoplastic Disease 2 40.72 Quite Low
Reprotox - General 1 1 39.76 Quite Low
Squamous Cell Carcinoma 1 37.04 Quite Low
Osteogenic Sarcomas 20 21.76 Low Low
Cancer 10 8.88 Low Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Bone Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
KHOSR2 cells treated with MDR1 siRNA loaded nanoparticles showed increased accumulation of the P-gp substrate calcein-AM by enhancing the uptake and/or decreasing the efflux of these compounds.
Positive_regulation (increased) of Positive_regulation (accumulation) of P-gp
1) Confidence 0.68 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2875382 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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