INT311843

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.85
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Smr3a)
Anatomy Link Frequency
submandibular glands 2
sympathetic 1
parasympathetic 1
Smr3a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 116 98.08 Very High Very High Very High
Spinal cord 4 90.04 High High
agonist 40 5.00 Very Low Very Low Very Low
complementary and alternative medicine 40 5.00 Very Low Very Low Very Low
cytokine 28 5.00 Very Low Very Low Very Low
corticosteroid 20 5.00 Very Low Very Low Very Low
Kinase C 16 5.00 Very Low Very Low Very Low
substance P 16 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 120 98.08 Very High Very High Very High
Hypersensitivity 376 97.56 Very High Very High Very High
Pneumonia 8 97.16 Very High Very High Very High
Anaphylaxis 64 96.08 Very High Very High Very High
Salivary Gland Disease 4 96.00 Very High Very High Very High
Stress 88 91.96 High High
Frailty 4 90.32 High High
Pancreatitis 4 89.36 High High
Sepsis 4 88.80 High High
Food Hypersensitivity 8 88.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In rats, a cleavage product of the prohormone SMR1 (submandibular rat 1) is produced in the submandibular gland and acts systemically to decrease allergic pulmonary inflammation and anaphylaxis.
Gene_expression (produced) of SMR1 in submandibular gland associated with inflammation, anaphylaxis, hypersensitivity and pneumonia
1) Confidence 0.13 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 1.29 Pain Relevance 0.23
SMR1 is present in rat submandibular glands in at least 52 species that result in part from N-glycosylation and cleavage of the protein.
Gene_expression (present) of SMR1 in submandibular glands
2) Confidence 0.12 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 1.17 Pain Relevance 0.23
We have evaluated the effect of sympathetic and parasympathetic mimetics on the expression, processing, and secretion of SMR1 in rats.
Gene_expression (expression) of SMR1 in parasympathetic
3) Confidence 0.12 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 1.20 Pain Relevance 0.23
We have evaluated the effect of sympathetic and parasympathetic mimetics on the expression, processing, and secretion of SMR1 in rats.
Gene_expression (expression) of SMR1 in sympathetic
4) Confidence 0.04 Published 2007 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2875553 Disease Relevance 1.20 Pain Relevance 0.23

General Comments

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