INT311886

Context Info Confidence 0.40 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.70 Pain Relevance 0.19

cell differentiation (Tgfbr1) signal transduction (Tgfbr1) cell motility (Tgfbr1) plasma membrane (Tgfbr1) embryo development (Tgfbr1) protein complex (Tgfbr1)

Anatomy Link Frequency articular cartilage 1 Tgfbr1 (Mus musculus)

Pain Link Frequency Relevance Heat Osteoarthritis 91 97.36 cytokine 5 5.00 metalloproteinase 3 5.00 fibrosis 2 5.00 Inflammation 1 5.00 Arthritis 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Osteoarthritis 96 97.36 Aging 13 96.08 Disease 12 79.28 Apoptosis 1 48.52 Hypertrophy 5 5.00 Fibrosis 2 5.00 Arthropathy 2 5.00 Osteophyte 1 5.00 Arthritis 1 5.00 Necrosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

type I receptor ALK5 and phosphorylation of Smad2/3 in murine articular cartilage [84].

Phosphorylation (phosphorylation) of ALK5 in articular cartilage

1) Confidence 0.40 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.70 Pain Relevance 0.19

General Comments

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