INT311905

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.46
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx2, Smad1) cytoplasm (Runx2, Smad1) homeostatic process (Smad1)
intracellular (Smad1) DNA binding (Runx2) transcription factor binding (Runx2)
Runx2 (Mus musculus)
Smad1 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 91 76.72 Quite High
cytokine 5 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 13 78.64 Quite High
Osteoarthritis 96 76.72 Quite High
Apoptosis 1 64.60 Quite High
Disease 12 47.68 Quite Low
Hypertrophy 5 5.00 Very Low Very Low Very Low
Fibrosis 2 5.00 Very Low Very Low Very Low
Arthropathy 2 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interaction of Runx2 with Smad1 facilitates the function of Runx2 in stimulating terminal differentiation, while Smad3 blocks Runx2 function [81-83].
Runx2 Binding (Interaction) of Smad1
1) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.46 Pain Relevance 0.13

General Comments

This test has worked.

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