INT311906

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Smad4) nucleus (Smad4) intracellular (Smad4)
DNA binding (Smad4) kinase activity (Insrr) protein complex (Smad4)
Anatomy Link Frequency
nucleus 1
Smad4 (Mus musculus)
Insrr (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 91 61.64 Quite High
metalloproteinase 3 23.44 Low Low
cytokine 5 15.12 Low Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 96 61.64 Quite High
Aging 13 61.36 Quite High
Disease 12 15.12 Low Low
Hypertrophy 5 5.00 Very Low Very Low Very Low
Fibrosis 2 5.00 Very Low Very Low Very Low
Arthropathy 2 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activated receptor Smads form a complex with the co-Smad, Smad4 - this complex translocates to the nucleus and modifies gene expression.
Smad4 Binding (form) of receptor in nucleus
1) Confidence 0.00 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875624 Disease Relevance 0.18 Pain Relevance 0.06

General Comments

This test has worked.

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