INT311965

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.33
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serping1) extracellular region (Serping1) molecular_function (Serping1)
cellular_component (Serping1) biological_process (Serping1)
Serping1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Infliximab 13 82.64 Quite High
Inflammation 6 69.04 Quite High
bradykinin 4 68.48 Quite High
cytokine 3 68.00 Quite High
antagonist 4 66.88 Quite High
rheumatoid arthritis 38 66.72 Quite High
Antihistamine 1 45.40 Quite Low
abdominal pain 2 37.28 Quite Low
Peripheral nervous system 1 19.96 Low Low
depression 1 17.80 Low Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 95 98.04 Very High Very High Very High
Emergencies 15 94.00 High High
Disease 18 90.08 High High
Stupor 1 83.92 Quite High
INFLAMMATION 9 69.04 Quite High
Rheumatoid Arthritis 38 66.72 Quite High
Hereditary Angioedema 36 52.36 Quite High
Vomiting 4 38.72 Quite Low
Abdominal Pain 2 37.28 Quite Low
Congenital Anomalies 2 28.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For three other IFN response genes (Mx2, OAS2, and SERPING1), a trend (P = approximately 0.06, data not shown) was observed toward increased expression in the poor responder patients.
Positive_regulation (increased) of Gene_expression (expression) of SERPING1
1) Confidence 0.16 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875639 Disease Relevance 0.19 Pain Relevance 0.17
Medication to relieve acute edematous attacks should also be provided (such as C1-INH) - regardless of whether or not the patient has already experienced a severe episode previously.

4.2 Management of UAE event

Spec (whether) Positive_regulation (experienced) of Neg (not) Gene_expression (provided) of C1-INH associated with pressure and volume under development
2) Confidence 0.06 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2920238 Disease Relevance 1.14 Pain Relevance 0.07

General Comments

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