INT312100

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ELANE, EGR1) nucleoplasm (EGR1) peptidase activity (ELANE)
extracellular region (ELANE) nucleus (EGR1) intracellular (EGR1)
ELANE (Homo sapiens)
EGR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 3 95.40 Very High Very High Very High
Inflammation 17 61.80 Quite High
Osteoarthritis 44 60.56 Quite High
alcohol 1 43.24 Quite Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
licofelone 3 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 61.80 Quite High
Osteoarthritis 48 60.56 Quite High
Disease 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Pathologic Processes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hypothesized that the induction of Egr-1 activity by HNE could be the mechanism by which HNE exerts its stimulatory effect on mPGES-1 transcription.
HNE Positive_regulation (induction) of Egr-1 Binding (activity) of
1) Confidence 0.16 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875653 Disease Relevance 0.23 Pain Relevance 0.16

General Comments

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