INT312107

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (COX18) mitochondrion (COX18) peptidase activity (ELANE)
extracellular region (ELANE) cytoplasm (ELANE)
ELANE (Homo sapiens)
COX18 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 44 20.40 Low Low
Inflammation 17 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
licofelone 3 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 48 50.00 Quite Low
Apoptosis 1 46.08 Quite Low
INFLAMMATION 22 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Pathologic Processes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M HNE showed an increase in COX-2 protein expression and PGE2 release within 2 hours and plateaued at 8 hours of incubation, before declining at 16 hours and 24 hours (Figure 1a, b).
HNE Positive_regulation (increase) of Gene_expression (expression) of COX-2 protein
1) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875653 Disease Relevance 0 Pain Relevance 0

General Comments

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