INT312116

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (ALOX5AP) endoplasmic reticulum (ALOX5AP) nucleus (ALOX5AP)
plasma membrane (PTGER2) enzyme binding (ALOX5AP) signal transducer activity (PTGER2)
PTGER2 (Homo sapiens)
ALOX5AP (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 44 91.12 High High
Inflammatory response 2 58.72 Quite High
Inflammatory mediators 1 53.44 Quite High
Arthritis 2 46.24 Quite Low
Pain 1 35.20 Quite Low
cINOD 2 31.04 Quite Low
COX-2 inhibitor 2 6.16 Low Low
Inflammation 17 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 48 91.12 High High
INFLAMMATION 22 58.72 Quite High
Arthritis 2 46.24 Quite Low
Pain 1 35.20 Quite Low
Disease 3 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Pathologic Processes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PGE2 inhibition regulates 5-LOX and FLAP expression differentially.
Negative_regulation (inhibition) of PGE2 Regulation (regulates) of Gene_expression (expression) of FLAP
1) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875653 Disease Relevance 0.20 Pain Relevance 0.10

General Comments

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