INT31218

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Context Info
Confidence 0.44
First Reported 1987
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.15
Pain Relevance 2.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Man2a2)
Anatomy Link Frequency
BSTV 4
Man2a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 10 100.00 Very High Very High Very High
noradrenaline 18 99.24 Very High Very High Very High
Clonidine 8 97.48 Very High Very High Very High
agonist 13 97.08 Very High Very High Very High
amygdala 1 93.88 High High
anticonvulsant 1 30.72 Quite Low
Disease Link Frequency Relevance Heat
Convulsion 3 88.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present results demonstrate that alpha 2 autoreceptors are a major mechanism in the control of NA efflux in the BSTV.
Regulation (major) of Gene_expression (mechanism) of alpha 2 in BSTV associated with noradrenaline
1) Confidence 0.44 Published 1993 Journal Brain Res. Section Abstract Doc Link 8097660 Disease Relevance 0 Pain Relevance 0.76
The present results demonstrate that alpha 2 autoreceptors are a major mechanism in the control of NA efflux in the BSTV.
Regulation (demonstrate) of Gene_expression (mechanism) of alpha 2 in BSTV associated with noradrenaline
2) Confidence 0.44 Published 1993 Journal Brain Res. Section Abstract Doc Link 8097660 Disease Relevance 0 Pain Relevance 0.76
The facilitation was selective for alpha-2 antagonists because neither the alpha-1 antagonist corynanthine (0.1-10.0 mg/kg i.p.), nor the beta antagonist propranolol (0.1-10.0 mg/kg i.p.), nor the selective beta-1 antagonist ICI 89,406 (10 micrograms/40 microliter i.c.v.) nor the beta-2 antagonist ICI 118,551 (0.5-5.0 mg/kg i.p.) modified kindling development.
Regulation (selective) of Gene_expression (antagonists) of alpha-2 associated with antagonist
3) Confidence 0.43 Published 1987 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2885413 Disease Relevance 0.15 Pain Relevance 0.62

General Comments

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