INT312226

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (INPP5K) signal transduction (IGFBP5) extracellular region (IGFBP5)
endoplasmic reticulum (INPP5K) plasma membrane (INPP5K) nucleus (INPP5K)
INPP5K (Homo sapiens)
IGFBP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 2 92.40 High High
Osteoarthritis 5 48.96 Quite Low
antagonist 1 21.68 Low Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 11 73.36 Quite High
Osteoarthritis 7 48.96 Quite Low
Disease Progression 1 34.56 Quite Low
Obesity 3 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Fibrosis 1 5.00 Very Low Very Low Very Low
Osteophyte 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/ml significantly increased MPC expression of IGFBP-3; however, IGFBP-5 was only weakly expressed and marginally upregulated by PPS (data not shown).
PPS Positive_regulation (upregulated) of IGFBP-5
1) Confidence 0.12 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875662 Disease Relevance 0.07 Pain Relevance 0.05

General Comments

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