INT312284

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.30
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Comp) extracellular region (Comp) cell adhesion (Comp)
proteinaceous extracellular matrix (Comp) extracellular matrix organization (Comp)
Comp (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 6 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscle Disease 69 99.66 Very High Very High Very High
Osteochondrodysplasias 81 98.68 Very High Very High Very High
Stress 15 94.80 High High
Targeted Disruption 15 89.52 High High
Necrosis 3 87.88 High High
Muscle Weakness 21 86.48 High High
Disease 48 84.24 Quite High
Death 3 81.52 Quite High
Cleidocranial Dysplasia 27 74.20 Quite High
Tendinopathy 3 66.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The T3 and CTD domains of COMP can form intramolecular interactions as demonstrated by the recent crystal structure model [72, 73].
COMP Binding (interactions) of
1) Confidence 0.30 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2875749 Disease Relevance 0.76 Pain Relevance 0
It is therefore not surprising that other MED-causing mutations were found in genes encoding proteins known to interact with COMP such as matrilin-3 and type IX collagen, although the precise rationale for this genetic heterogeneity of MED has yet to be determined.
COMP Binding (interact) of associated with osteochondrodysplasias
2) Confidence 0.30 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2875749 Disease Relevance 1.30 Pain Relevance 0
To test the hypothesis that myopathy is specifically associated with CTD-COMP mutations localised near the potential collagen and integrin binding sites, we have investigated a second mouse model, COMP ?
CTD-COMP Binding (associated) of associated with muscle disease
3) Confidence 0.30 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2875749 Disease Relevance 1.02 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox