INT312303

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Context Info
Confidence 0.38
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (FLT1, VEGFA) extracellular space (FLT1, VEGFA) extracellular region (FLT1, VEGFA)
cell differentiation (FLT1) endosome (FLT1) Golgi apparatus (FLT1)
Anatomy Link Frequency
endothelial cells 2
FLT1 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 52.28 Quite High
dexamethasone 5 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibromyalgia 1 87.28 High High
Cancer 24 82.04 Quite High
Solid Tumor 8 74.32 Quite High
Hypoxia 4 64.80 Quite High
Adenocarcinoma 1 62.84 Quite High
Glioma 1 57.68 Quite High
Necrosis 1 55.88 Quite High
Hypoglycemia 1 46.36 Quite Low
Targeted Disruption 1 12.00 Low Low
Embryonic Lethality 1 10.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VEGFR-1 (ligands include VEGF-A, -B, and placental growth factor [PIGF]) and VEGFR-2 (ligands include VEGF-A, -C, and -D) are predominantly expressed on vascular endothelial cells, and activation of VEGFR-2 appears to be both necessary and sufficient to mediate VEGF-dependent angiogenesis and induction of vascular permeability [13, 14].
Positive_regulation (activation) of VEGFR-2 in endothelial cells Positive_regulation (mediate) of VEGF-dependent
1) Confidence 0.38 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2875768 Disease Relevance 0.73 Pain Relevance 0.03

General Comments

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