INT312519

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.46
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARA) small molecule metabolic process (PPARA) lyase activity (DAK)
DNA binding (PPARA) lipid metabolic process (PPARA) cytosol (DAK)
Anatomy Link Frequency
retina 2
DAK (Homo sapiens)
PPARA (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 10 90.08 High High
Inflammation 96 87.68 High High
cINOD 46 11.04 Low Low
Hippocampus 18 5.00 Very Low Very Low Very Low
positron emission tomography 10 5.00 Very Low Very Low Very Low
cytokine 10 5.00 Very Low Very Low Very Low
long-term potentiation 6 5.00 Very Low Very Low Very Low
Bioavailability 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 102 87.68 High High
Aging 14 85.68 High High
Vascular Dementia 2 81.72 Quite High
Disease 254 80.84 Quite High
Cognitive Disorder 100 56.24 Quite High
Neurodegenerative Disease 20 55.32 Quite High
Apoptosis 4 49.68 Quite Low
Alzheimer's Dementia 78 36.00 Quite Low
Cancer 18 5.00 Very Low Very Low Very Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While this effect has been established in the retina [156], it may also be important in neuroprotection [157].DHA can activate both peroxisome proliferator-activated receptor (PPAR) and nuclear retinoid X receptor alpha (RXRalpha), involved in the regulation of lipid biosynthesis [158, 159].
DHA Positive_regulation (activate) of PPAR in retina
1) Confidence 0.00 Published 2010 Journal Mol Neurobiol Section Body Doc Link PMC2876259 Disease Relevance 0.73 Pain Relevance 0.09
While this effect has been established in the retina [156], it may also be important in neuroprotection [157].DHA can activate both peroxisome proliferator-activated receptor (PPAR) and nuclear retinoid X receptor alpha (RXRalpha), involved in the regulation of lipid biosynthesis [158, 159].
DHA Positive_regulation (activate) of peroxisome proliferator-activated receptor in retina
2) Confidence 0.00 Published 2010 Journal Mol Neurobiol Section Body Doc Link PMC2876259 Disease Relevance 0.73 Pain Relevance 0.09

General Comments

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