INT312609

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.52
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Dok7) plasma membrane (Dok7)
Dok7 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
Action potential 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Myasthenic Syndromes 44 97.96 Very High Very High Very High
Congenital Anomalies 4 66.72 Quite High
Myasthenia Gravis 6 5.00 Very Low Very Low Very Low
Syndrome 6 5.00 Very Low Very Low Very Low
Respiratory Failure 4 5.00 Very Low Very Low Very Low
Muscle Weakness 4 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our expression studies have identified impairment of MuSK phosphorylation and MuSKĀ–Dok-7 interaction as central to the pathogenesis of the CMS described here.
Negative_regulation (impairment) of Phosphorylation (phosphorylation) of Dok-7 associated with congenital myasthenic syndromes
1) Confidence 0.37 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.24 Pain Relevance 0
In contrast, M605I results in moderate impairment of both phosphorylation and binding to Dok-7.
Negative_regulation (impairment) of Phosphorylation (phosphorylation) of Dok-7
2) Confidence 0.37 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.28 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox